Edward S.Simko;65;of Fayette City died Tuesday morning;Sept.18;1979;at the Mon Valley Hospital.   He was born in Fayette City on March 28;1914;the son of the late George and Julia Sivak Simko.  He was a member of the Holy Spirit Roman Catholic Church;Fayette City;and the Loyal Order of the Moose;Lodge No.92;Perryopolis.  Mr.Simko was retired from the Wheeling Pittsburgh Steel Corp.;Allenport Plant.  He is survived by his wife Barbara Plavetich Simko;a daughter;Mrs.Patsy (Barbara Ann) DeRinzo;of Belle Vernon;a brother;George Simko;of Lincoln Park;Mich.;two sisters;Mrs.Paul (Irene) Lape;of Belle Vernon;and Mrs.William (Margaret) Luckasevic;of Charleroi;and two grandsosns;Patrick and Matthew DeRinzo.  Friends will be received at the Howard W.McCrory Funeral Home;Fayette City;after 7 p.m. on Wednesday where Prayer services will be held Friday at 9:30 a.m.  A Mass of Christian Burial will be conducted on Friday at 10 a.m.at Holy Spirit Catholic Church with the Rev.Father Thomas G.Rinn officiating.  Burial will be in Belle Vernon Cemetery.